منابع مشابه
Polypharmacy versus Drug Combinations
Drug combinations have been known to be used either for increasing effcctivity or for decreasing side-efFects. It is only when multiple drugs are prescribed without adequate scientific evidence in their favour then such practices need careful scrutiny. Multiple drug use in psychiatry has recently gained currency and so require thoughtful consideration. The term polypharmacy is generally used to...
متن کاملEvaluation of several drug combinations for intraperitoneal anaesthesia in adult male rats
The objective of this study was to evaluate several drug combinations for intraperitoneal anaesthesia in laboratory rats. Following dose determination of anaesthetics in a pilot study, 45 healthy adult male rats were randomly assigned in 9 treatment groups and received propofol (alone or in combination with xylazine, midazolam, or ketamine) or ketamine (in combination with xylazine, midazolam, ...
متن کاملDrug interactions and lethal drug combinations.
Although the development of drugs of greater potency and efficacy confers on the physician increasing power to treat serious diseases, it also increases the number and seriousness of potential adverse effects and drug interactions which can occur. Most hospital patients receive more than one drug at a time, the average number often being greater than five (Smith, Seidl, and Cluff, 1966). The in...
متن کاملDrug repurposing screens and synergistic drug‐combinations for infectious diseases
Infectious diseases account for nearly one fifth of the worldwide death toll every year. The continuous increase of drug-resistant pathogens is a big challenge for treatment of infectious diseases. In addition, outbreaks of infections and new pathogens are potential threats to public health. Lack of effective treatments for drug-resistant bacteria and recent outbreaks of Ebola and Zika viral in...
متن کاملDangerous and Deadly Drug Combinations Drug Interaction Checker
Drug/drug interactions are considered preventable errors. With the advent of electronic prescribing, the hope was that software would warn prescribers about interactions between one or more drugs that the patient is taking, and these alerts are common. They are so ubiquitous, in fact, that alerts are often overridden in the prescribing process. Clinicians cannot rely on prescribing software to ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Science
سال: 2018
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.361.6397.39-b